(1S,3S)-3-Aminocyclopentanol hydrochloride

Name: (1S,3S)-3-Aminocyclopentanol hydrochloride
Brand: ChemScene
Availability: InStock
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CAS No. 1523530-42-8
Cat. No. CS-0053559
Purity≥97%
MDL No.MFCD23704943

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(1S,3S)-3-Aminocyclopentanol hydrochloride|CS-0053559

Structure of 1523530-42-8

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Description

(1S,3S)-3-Aminocyclopentanol hydrochloride is a chiral, bench-stable amino alcohol featuring a rigid cyclopentane backbone with stereochemically defined (1S,3S) configuration. This configuration positions the amine and hydroxyl groups in a favorable proximal arrangement, enabling efficient coordination in asymmetric synthesis. The hydrochloride salt enhances solubility and stability for handling in aqueous or polar organic media.

Application

(1S,3S)-3-Aminocyclopentanol hydrochloride serves as a stereochemically defined building block for the synthesis of bioactive heterocycles and conformationally constrained peptidomimetics. The chiral amine functionality enables direct incorporation into medicinal chemistry libraries via standard coupling reactions, while the cyclopentanol scaffold provides rigidity and favorable physicochemical properties. Bench-stable and readily purified by recrystallization, it functions as a versatile intermediate in asymmetric synthesis workflows requiring controlled stereochemistry and functional group compatibility.

General Information

CAS No. 1523530-42-8
Cat. No. CS-0053559
Purity ≥97%
MDL No. MFCD23704943
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₂ClNO
Molecular Weight 137.61
Synonym(s) (1S,3S)-3-AMINOCYCLOPENTANOL HCL
SMILES N[C@H]1CC[C@@H](C1)O.Cl

Computational Chemistry Data

TPSA 46.25
LogP 0.2803
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Fatty ring compounds Cyclopentane compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(1S,3S)-3-Aminocyclopentanol hydrochloride

CAS No. 1523530-42-8

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