3-Aminopyridine-4-methanol

Name: 3-Aminopyridine-4-methanol
Brand: ChemScene
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CAS No. 152398-05-5
Cat. No. CS-0157313
Purity≥98%
MDL No.MFCD06658330

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Description

3-Aminopyridine-4-methanol integrates a primary amine and hydroxymethyl group on a pyridine scaffold, enabling versatile functionalization in medicinal chemistry. This bifunctional heterocycle supports conjugation strategies and serves as a key intermediate in targeted synthesis workflows.

Application

3-Aminopyridine-4-methanol serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds via nucleophilic substitution and coupling reactions. Its dual functionality—primary amine and primary alcohol—facilitates orthogonal derivatization, while the pyridine core enhances solubility and binding affinity in target-directed synthesis. Bench-stable and readily purified by crystallization, it functions efficiently in standard peptide coupling and transition-metal-catalyzed transformations.

General Information

CAS No. 152398-05-5
Cat. No. CS-0157313
Purity ≥98%
MDL No. MFCD06658330
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₈N₂O
Molecular Weight 124.14
Synonym(s) (3-Aminopyridin-4-yl)methanol
SMILES C1=C(CO)C(=CN=C1)N

Computational Chemistry Data

TPSA 59.14
LogP 0.1561
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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3-Aminopyridine-4-methanol

CAS No. 152398-05-5

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