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Structure of 152626-78-3
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5-Bromo-6-methoxy-1H-indazole is a heterocyclic scaffold featuring a bromine atom at the 5-position and a methoxy group at the 6-position, providing orthogonal reactivity for cross-coupling and derivatization. This electron-deficient indazole integrates readily into bioactive molecules, offering enhanced metabolic stability and tunable solubility in polar solvents.
5-Bromo-6-methoxy-1H-indazole serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C5 position via palladium-catalyzed cross-coupling reactions. The methoxy group provides moderate electron donation and enhances solubility, while the indazole core offers metabolic stability and favorable binding interactions in target-directed synthesis. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for iterative library construction and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: