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Structure of 53857-57-1
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5-Bromo-1H-indazole is a heterocyclic compound featuring a bromine substituent at the 5-position of the indazole scaffold. This electron-deficient aryl halide enables direct functionalization in cross-coupling reactions, facilitating the synthesis of complex biaryl architectures. The molecule exhibits enhanced stability under standard bench conditions and demonstrates favorable solubility in common organic solvents, making it a reliable building block for medicinal chemistry and materials science applications.
5-Bromo-1H-indazole serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions for the construction of biologically relevant heterocyclic scaffolds. The bromine substituent facilitates reliable C–C bond formation under standard Suzuki, Stille, or Negishi conditions, while the indazole core provides a stable, planar platform with moderate hydrogen-bonding capacity. Its bench-stable crystalline form supports straightforward handling and purification, making it well-suited for iterative synthesis campaigns in drug discovery.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: