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Structure of 15288-53-6
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2-(Trimethylsilyl)phenol serves as a stable, moisture-tolerant phenolic building block featuring a bulky trimethylsilyl group that enhances solubility and protects the hydroxyl functionality. This silyl ether derivative facilitates selective transformations in synthetic sequences and integrates seamlessly into complex molecular architectures under standard conditions.
2-(Trimethylsilyl)phenol serves as a stable, bench-friendly phenolic building block enabling regioselective functionalization via silyl group activation. Its ortho-trimethylsilyl moiety facilitates directed metalation and acts as a temporary protecting group for hydroxyl functionality during multi-step syntheses. The compound exhibits excellent compatibility with common coupling reactions and provides straightforward desilylation under mild basic conditions, making it valuable for constructing complex aromatic scaffolds in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3265
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: