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CS-W001157 4
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5-Ethynylfuran-2-carbaldehyde

  • CAS No. 153026-71-2

  • Cat. No. CS-0122349
  • Purity≥97%
  • MDL No.MFCD17168298

*For research and further manufacturing use only, not for direct human use.

5-Ethynylfuran-2-carbaldehyde|CS-0122349

Structure of 153026-71-2

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General Information

  • CAS No. 153026-71-2
  • Cat. No. CS-0122349
  • Purity ≥97%
  • MDL No. MFCD17168298
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄O₂
  • Molecular Weight 120.11
  • Synonym(s) 5-ethynylfuran-2-carbaldehyde 5-ethynylfuran-2-carbaldehyde
  • SMILES O=CC1=CC=C(C#C)O1

Description

5-Ethynylfuran-2-carbaldehyde features a conjugated alkyne and aldehyde pair within a furan scaffold, enabling efficient copper-catalyzed click chemistry. This bifunctional motif integrates readily into complex architectures, offering high reactivity under mild conditions with excellent functional group tolerance.

Application

5-Ethynylfuran-2-carbaldehyde serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted furan derivatives via copper-catalyzed azide-alkyne cycloaddition (CuAAC) and other transition-metal-catalyzed coupling reactions. The conjugated aldehyde and terminal alkyne functionalities offer orthogonal reactivity for sequential functionalization, facilitating the construction of complex heterocyclic scaffolds. Bench-stable and compatible with standard purification protocols, it functions effectively in multistep syntheses targeting bioactive molecules and advanced intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   30.21
  • LogP   1.0734
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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