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Structure of 153181-07-8
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(S)-2-Amino-3-(4-(trifluoromethyl)phenyl)propan-1-ol is a chiral building block featuring a benzene ring substituted with a trifluoromethyl group and a pendant amino-alcohol functionality. This configuration enables selective incorporation into bioactive scaffolds, particularly in medicinal chemistry applications where stereochemical control is critical. The molecule exhibits enhanced metabolic stability due to the electron-withdrawing trifluoromethyl moiety and demonstrates favorable solubility under standard reaction conditions.
(S)-2-Amino-3-(4-(trifluoromethyl)phenyl)propan-1-ol serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules via standard amine and alcohol functional group transformations. Its structural features—chirality, aromatic trifluoromethyl group, and orthogonal functionality—support efficient coupling reactions, derivatization, and incorporation into heterocyclic scaffolds. Bench-stable and compatible with common protecting group strategies, it facilitates scalable route development for API candidates requiring defined stereochemistry and enhanced metabolic stability.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: