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CS-W001157 4
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Ethyl 2-(1-methylguanidino)acetate hydrochloride

  • CAS No. 15366-32-2

  • Cat. No. CS-W022641
  • Purity≥95%
  • MDL No.MFCD08704792

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-(1-methylguanidino)acetate hydrochloride|CS-W022641

Structure of 15366-32-2

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General Information

  • CAS No. 15366-32-2
  • Cat. No. CS-W022641
  • Purity ≥95%
  • MDL No. MFCD08704792
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₄ClN₃O₂
  • Molecular Weight 195.65
  • Synonym(s) Creatine Ethyl Ester HCL
  • SMILES O=C(OCC)CN(C)C(N)=N.[H]Cl

Description

Ethyl 2-(1-methylguanidino)acetate hydrochloride features a protonated guanidino group that enhances solubility and stability in aqueous media. This salt form facilitates handling and integration into peptide synthesis workflows, where it serves as a key building block for arginine mimetics. The ethyl ester moiety enables further derivatization under standard coupling conditions.

Application

Ethyl 2-(1-methylguanidino)acetate hydrochloride serves as a versatile building block for synthesizing guanidine-containing scaffolds relevant to medicinal chemistry. Its stable, crystalline form enables straightforward handling and purification, while the methylguanidino group exhibits predictable reactivity in amide bond formation and heterocycle construction. Functions effectively in standard peptide coupling and derivatization workflows, offering reliable access to bioactive guanidine motifs under routine laboratory conditions.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   79.41
  • LogP   -0.20343
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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