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Structure of 153813-70-8
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3-Nitro-4-pyridinecarboxaldehyde features a conjugated pyridine core bearing both aldehyde and nitro functional groups, enabling direct coupling in cross-coupling reactions. The electron-deficient aldehyde facilitates nucleophilic addition, while the para-nitro group enhances reactivity in transition-metal-catalyzed transformations. This compound serves as a key building block for heterocyclic scaffolds in medicinal chemistry and materials science.
3-Nitro-4-pyridinecarboxaldehyde serves as a versatile building block in medicinal and synthetic chemistry, enabling efficient access to functionalized pyridine scaffolds. Its aldehyde group facilitates imine formation and reductive amination, while the ortho-nitro substituent supports electrophilic substitution and acts as a handle for subsequent reduction or coupling reactions. The molecule exhibits good bench stability and compatibility with standard purification techniques, making it well-suited for multi-step synthesis and process development workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: