4-Chloro-6-methylnicotinonitrile

Name: 4-Chloro-6-methylnicotinonitrile
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 38875-76-2
Cat. No. CS-D0529
Purity≥98%
MDL No.MFCD01078061

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Chloro-6-methylnicotinonitrile|CS-D0529

Structure of 38875-76-2

Size

Price

Quantity

* Please select Quantity before adding items.

Description

4-Chloro-6-methylnicotinonitrile features a pyridine core functionalized with chlorine, methyl, and nitrile groups, enabling selective coupling in heterocyclic synthesis. This electron-deficient scaffold integrates readily into pharmaceutical intermediates and agrochemical frameworks, offering robust stability under standard reaction conditions.

Application

4-Chloro-6-methylnicotinonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted pyridine scaffolds via cross-coupling and nucleophilic substitution reactions. The nitrile group facilitates downstream transformations to carboxylic acids or amides, while the chloro and methyl substituents provide orthogonal reactivity for sequential functionalization. Bench-stable and readily purified by recrystallization, it functions reliably in standard synthetic workflows.

General Information

CAS No. 38875-76-2
Cat. No. CS-D0529
Purity ≥98%
MDL No. MFCD01078061
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₅ClN₂
Molecular Weight 152.58
Synonym(s) 4-chloro-6-Methylpyridine-3-carbonitrile
SMILES N#CC1=CN=C(C)C=C1Cl

Computational Chemistry Data

TPSA 36.68
LogP 1.9151
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Cyanide/Nitrile

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

4-Chloro-6-methylnicotinonitrile sigma4-Chloro-6-methylnicotinonitrile manufacturer4-Chloro-6-methylnicotinonitrile price4-Chloro-6-methylnicotinonitrile structure4-Chloro-6-methylnicotinonitrile SDSbuy 4-Chloro-6-methylnicotinonitrile4-Chloro-6-methylnicotinonitrile supplier4-Chloro-6-methylnicotinonitrile uses4-Chloro-6-methylnicotinonitrile molecular weightprice of 4-Chloro-6-methylnicotinonitrile4-Chloro-6-methylnicotinonitrile chemical name formula of 4-Chloro-6-methylnicotinonitrile

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-Chloro-6-methylnicotinonitrile

CAS No. 38875-76-2

Recommended Products