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CS-W001157 4
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(3-Methylpyridin-2-yl)methanamine

  • CAS No. 153936-26-6

  • Cat. No. CS-0094519
  • Purity≥97%
  • MDL No.MFCD04116209

*For research and further manufacturing use only, not for direct human use.

(3-Methylpyridin-2-yl)methanamine|CS-0094519

Structure of 153936-26-6

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General Information

  • CAS No. 153936-26-6
  • Cat. No. CS-0094519
  • Purity ≥97%
  • MDL No. MFCD04116209
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀N₂
  • Molecular Weight 122.17
  • Synonym(s) 2-AMINOMETHYL-3-METHYLPYRIDINE
  • SMILES NCC1=NC=CC=C1C

Description

This bench-stable, moisture-tolerant amine features a pyridine ring with a methyl group at the 3-position and a methylene-attached primary amine at the 2-position. The electron-deficient heterocycle enhances nucleophilicity, enabling efficient coupling in transition-metal catalysis and synthetic route design.

Application

(3-Methylpyridin-2-yl)methanamine serves as a versatile building block in medicinal chemistry, enabling efficient construction of bioactive heterocycles through standard amine functionalization. Its pyridine nitrogen and methyl substituent provide favorable electronic and steric properties for metal-catalyzed coupling reactions, while the benzylic amine functionality offers robust reactivity in amide formation, reductive amination, and electrophilic substitution. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   0.84872
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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