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Structure of 153936-26-6
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This bench-stable, moisture-tolerant amine features a pyridine ring with a methyl group at the 3-position and a methylene-attached primary amine at the 2-position. The electron-deficient heterocycle enhances nucleophilicity, enabling efficient coupling in transition-metal catalysis and synthetic route design.
(3-Methylpyridin-2-yl)methanamine serves as a versatile building block in medicinal chemistry, enabling efficient construction of bioactive heterocycles through standard amine functionalization. Its pyridine nitrogen and methyl substituent provide favorable electronic and steric properties for metal-catalyzed coupling reactions, while the benzylic amine functionality offers robust reactivity in amide formation, reductive amination, and electrophilic substitution. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows in API development.
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H314
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Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: