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Structure of 1540204-53-2
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4-Bromo-2-fluoro-3-methylaniline features a trifunctional aromatic core with bromo, fluoro, and methyl groups positioned for orthogonal reactivity. This electron-deficient aniline derivative enables selective coupling in cross-coupling protocols and serves as a key intermediate in the synthesis of bioactive heterocycles and functional materials under standard conditions.
4-Bromo-2-fluoro-3-methylaniline serves as a valuable building block in the synthesis of pharmaceutical intermediates and functionalized heterocycles. Its ortho-fluoro and meta-bromo substituents provide orthogonal reactivity for palladium-catalyzed cross-coupling and electrophilic substitution, while the methyl group enhances metabolic stability in drug candidates. The compound exhibits good bench stability and is amenable to standard purification methods, facilitating integration into multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: