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Structure of 154825-97-5
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Methyl 2-(4-bromophenyl)-2,2-dimethylacetate is a bench-stable, moisture-tolerant building block featuring a sterically hindered quaternary carbon center. The para-bromophenyl group imparts enhanced reactivity in palladium-catalyzed cross-coupling processes, while the ester functionality enables straightforward derivatization. This compound integrates efficiently into complex molecular architectures requiring robust aryl-alkyl linkages.
Methyl 2-(4-bromophenyl)-2,2-dimethylacetate serves as a versatile building block for Suzuki-Miyaura coupling reactions, enabling efficient construction of biaryl scaffolds. The bromophenyl group exhibits high reactivity under standard palladium catalysis, while the sterically hindered gem-dimethylacetyl moiety provides excellent bench stability and facilitates straightforward purification. Its compatibility with diverse reaction conditions makes it a reliable intermediate in the synthesis of functionalized aromatic compounds and pharmaceutical precursors.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: