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CS-W001157 4
Total: USD 88.00

2,6-Difluoropyridine-3-carboxaldehyde

  • CAS No. 155601-65-3

  • Cat. No. CS-W003506
  • Purity≥98%
  • MDL No.MFCD08277633
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2,6-Difluoropyridine-3-carboxaldehyde|CS-W003506

Structure of 155601-65-3

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Description

2,6-Difluoropyridine-3-carboxaldehyde features a strategically positioned aldehyde group flanked by two fluorine atoms at the 2 and 6 positions of the pyridine ring. This electron-deficient heterocycle enables efficient coupling in transition-metal-catalyzed reactions and serves as a key building block for bioactive molecules and functional materials.

Application

2,6-Difluoropyridine-3-carboxaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient construction of fluorinated heterocyclic scaffolds. Its aldehyde functionality facilitates imine formation and reductive amination, while the ortho-fluorine substituents support nucleophilic aromatic substitution under mild conditions. The molecule exhibits good bench stability and compatibility with common protecting groups, making it suitable for multi-step synthesis and process-scale applications.

General Information

  • CAS No. 155601-65-3
  • Cat. No. CS-W003506
  • Purity ≥98%
  • MDL No. MFCD08277633
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃F₂NO
  • Molecular Weight 143.09
  • Synonym(s) 2,6-Difluoronicotinaldehyde
  • SMILES FC1=NC(F)=C(C=O)C=C1

Computational Chemistry Data

  • TPSA   29.96
  • LogP   1.1723
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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