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Structure of 1557138-33-6
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This boronate-functionalized indole integrates a trifluoromethyl group at the 6-position, enhancing electron deficiency and metabolic stability. The tetramethylborolane moiety enables efficient Suzuki-Miyaura coupling under mild conditions, facilitating rapid access to complex heterocycles in medicinal chemistry and materials science.
2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)-1H-indole serves as a versatile boronate building block in palladium-catalyzed cross-coupling reactions. The tetramethylboronate moiety enables efficient Suzuki-Miyaura coupling under mild conditions, while the trifluoromethyl group enhances metabolic stability and lipophilicity. Bench-stable and readily purified by flash chromatography, it facilitates the construction of complex biaryl scaffolds common in pharmaceutical research.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: