1-Acetylpiperidine-4-carbaldehyde

Name: 1-Acetylpiperidine-4-carbaldehyde
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 155826-26-9
Cat. No. CS-W006375
Purity≥98%
MDL No.MFCD11582881

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-Acetylpiperidine-4-carbaldehyde|CS-W006375

Structure of 155826-26-9

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 155826-26-9
Cat. No. CS-W006375
Purity ≥98%
MDL No. MFCD11582881
Storage -20°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₃NO₂
Molecular Weight 155.19
Synonym(s) N-acetylpiperidine-4-carbaldehyde
SMILES CC(=O)N1CCC(CC1)C=O

Description

1-Acetylpiperidine-4-carbaldehyde features a piperidine scaffold with acetyl and aldehyde functionalities at the 1- and 4-positions, respectively. This bifunctional motif enables direct incorporation into diversely functionalized scaffolds, serving as a key intermediate in medicinal chemistry. The aldehyde group facilitates conjugate additions and reductive aminations, while the acetyl moiety offers tunable polarity and metabolic stability under standard conditions.

Application

1-Acetylpiperidine-4-carbaldehyde serves as a versatile synthetic intermediate for constructing nitrogen-containing heterocycles and bioactive scaffolds. The aldehyde functionality enables efficient reductive amination, Grignard additions, and condensation reactions, while the acetyl group provides moderate stability and facilitates subsequent functionalization. Its bench-stable nature and compatibility with common protecting group strategies make it well-suited for iterative synthesis in medicinal chemistry and process development workflows.

Synthesis

Route1
- 69001-10-1
- ~%
- In-stock
  
  155826-26-9
References
- Kazmierski, Wieslaw M.; Maynard, Andrew; Duan, Maosheng; Baskaran, Sam; Botyanszki, Janos; Crosby, Renae; Dickerson, Scott; Tallant, Matthew; Grimes, Rick; Hamatake, Robert; Leivers, Martin; Roberts, Christopher D.; Walker, Jill Journal of Medicinal Chemistry, 2014 , vol. 57, # 5 p. 2058 - 2073

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 37.38
LogP 0.4438
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Key Words

1-Acetylpiperidine-4-carbaldehyde sigma1-Acetylpiperidine-4-carbaldehyde manufacturer1-Acetylpiperidine-4-carbaldehyde price1-Acetylpiperidine-4-carbaldehyde structure1-Acetylpiperidine-4-carbaldehyde SDSbuy 1-Acetylpiperidine-4-carbaldehyde1-Acetylpiperidine-4-carbaldehyde supplier1-Acetylpiperidine-4-carbaldehyde uses1-Acetylpiperidine-4-carbaldehyde molecular weightprice of 1-Acetylpiperidine-4-carbaldehyde1-Acetylpiperidine-4-carbaldehyde chemical name formula of 1-Acetylpiperidine-4-carbaldehyde

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1-Acetylpiperidine-4-carbaldehyde

CAS No. 155826-26-9

Recommended Products