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Structure of 1564709-36-9
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4-Ethyl-2-methyloxazole-5-carboxylic acid features a fused oxazole ring system with strategically positioned alkyl and carboxylic acid groups. This arrangement enables direct incorporation into bioactive scaffolds, offering enhanced metabolic stability and solubility in polar reaction media. The electron-deficient oxazole core facilitates nucleophilic substitution under mild conditions.
4-Ethyl-2-methyloxazole-5-carboxylic acid serves as a versatile heterocyclic building block in medicinal chemistry and synthetic organic research. Its carboxylic acid functionality enables direct amidation, esterification, and coupling reactions, while the oxazole ring provides metabolic stability and favorable physicochemical properties. The ethyl and methyl substituents enhance lipophilicity and offer defined steric profiles, facilitating predictable reactivity in scaffold diversification. This compound exhibits good bench stability and is amenable to standard purification methods, making it well-suited for use in multi-step synthesis and library generation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: