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Structure of 158387-20-3
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5-Chloro-6-methoxypyridin-3-amine integrates a chlorine substituent and a methoxy group on a pyridine scaffold, delivering enhanced electron-withdrawing character and improved solubility. This bench-stable heterocycle serves as a key building block in medicinal chemistry, enabling efficient coupling reactions for targeted synthesis of bioactive compounds.
5-Chloro-6-methoxypyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyridine-based scaffolds. Its ortho-chloro and amine functionalities facilitate palladium-catalyzed cross-coupling reactions and nucleophilic substitutions, while the methoxy group offers moderate stability and tunable reactivity. The compound exhibits excellent bench stability and is readily purified by standard chromatographic methods, making it well-suited for scalable synthesis and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: