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CS-W001157 4
Total: USD 88.00

6-Bromobenzo[d][1,3]dioxole-5-carbaldehyde

  • CAS No. 15930-53-7

  • Cat. No. CS-W005335
  • Purity≥98%
  • MDL No.MFCD00022952

*For research and further manufacturing use only, not for direct human use.

6-Bromobenzo[d][1,3]dioxole-5-carbaldehyde|CS-W005335

Structure of 15930-53-7

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General Information

  • CAS No. 15930-53-7
  • Cat. No. CS-W005335
  • Purity ≥98%
  • MDL No. MFCD00022952
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅BrO₃
  • Molecular Weight 229.03
  • Synonym(s) 6-Bromopiperonal
  • SMILES O=CC1=C(Br)C=C(OCO2)C2=C1

Description

N-(Amino-PEG4)-N-Biotin-PEG4-acid is a 3-arm biotinylation reagent with terminal amine(NH2) and carboxylic acid moieties. The amine group can react with activated NHS esters. Carboxylic acid can conjugate with primary amines in the presence of activators such as EDC or HATU to form stable amide bonds.

Synthesis

  • Route1
    • null|null
      120-57-0
    • ~93%
    • In-stock
      6-Bromobenzo[d][1,3]dioxole-5-carbaldehyde|CS-W005335
      15930-53-7

    References

    • Beck, Daniel E.; Agama, Keli; Marchand, Christophe; Chergui, Adel; Pommier, Yves; Cushman, Mark Journal of Medicinal Chemistry, 2014 , vol. 57, # 4 p. 1495 - 1512
  • Route2

    References

    • Li, Zhongzhou; Zhu, Wei; Bao, Jinlong; Zou, Xinzhuo Synthetic Communications, 2014 , vol. 44, # 8 p. 1155 - 1164
  • Route3
    • null|null
      74-97-5
    • In-stock
      2-Bromo-4,5-dihydroxybenzaldehyde|CS-0498421
      4815-99-0
    • ~86%
    • In-stock
      6-Bromobenzo[d][1,3]dioxole-5-carbaldehyde|CS-W005335
      15930-53-7

    References

    • Zelle; McClellan Tetrahedron Letters, 1991 , vol. 32, # 22 p. 2461 - 2464

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.53
  • LogP   1.9903
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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