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CS-W001157 4
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Fmoc-(S)-2-amino-3-methoxypropionic acid

  • CAS No. 159610-93-2

  • Cat. No. CS-0137339
  • Purity≥98%
  • MDL No.MFCD02682604
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Fmoc-(S)-2-amino-3-methoxypropionic acid|CS-0137339

Structure of 159610-93-2

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Description

Fmoc-(S)-2-amino-3-methoxypropionic acid is a specialized amino acid derivative featuring a methoxy group at the β-position, enhancing solubility and modulating electronic effects. This configuration supports efficient incorporation into peptide chains during solid-phase synthesis, offering improved handling and reduced aggregation. The Fmoc protecting group enables orthogonal deprotection, streamlining sequence assembly in complex peptide architectures.

Application

Fmoc-(S)-2-amino-3-methoxypropionic acid serves as a versatile building block in peptide synthesis, enabling the incorporation of β³-amino acid motifs with enhanced conformational diversity. The Fmoc group provides efficient orthogonal protection for the α-amino functionality, while the methoxy-substituted side chain offers improved solubility and metabolic stability. This derivative facilitates robust coupling reactions under standard conditions, supports facile deprotection, and functions effectively in solid-phase synthesis workflows.

General Information

  • CAS No. 159610-93-2
  • Cat. No. CS-0137339
  • Purity ≥98%
  • MDL No. MFCD02682604
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₁₉NO₅
  • Molecular Weight 341.36
  • Synonym(s) (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-methoxypropanoic acid
  • SMILES O=C(O)[C@H](COC)NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O

Computational Chemistry Data

  • TPSA   84.86
  • LogP   2.6247
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   6

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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