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Structure of 159749-28-7
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This azetidine derivative features a tert-butoxycarbonyl-protected amine and a carboxylic acid group, enabling direct incorporation into peptide chains. The strained four-membered ring imparts conformational rigidity, while the Boc group ensures stability during synthesis and purification.
1-(tert-Butoxycarbonyl)azetidine-2-carboxylic acid serves as a stable, bench-ready building block for the synthesis of bioactive azetidines. The Boc group provides excellent protection of the amine while enabling orthogonal deprotection under mild acidic conditions. It functions effectively in standard peptide coupling protocols and facilitates the construction of nitrogen-containing heterocycles, including key scaffolds in medicinal chemistry and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: