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Structure of 16034-46-1
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1-Methyl-5-pyrazolecarboxylic acid is a bench-stable, moisture-tolerant heterocyclic carboxylic acid featuring a methyl-substituted pyrazole core. This electron-deficient scaffold integrates readily into synthetic sequences requiring polar, nitrogen-rich functionalities. The carboxyl group enables direct coupling reactions or derivatization under standard conditions.
1-Methyl-5-pyrazolecarboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into bioactive heterocycles. Its pyrazole core exhibits favorable metabolic stability and hydrogen-bonding capacity, while the carboxylic acid functionality facilitates amide coupling, esterification, and salt formation under standard conditions. The methyl group enhances solubility and modulates electronic properties, supporting efficient synthesis of target molecules with predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: