1-Acetyl-4-aminopiperidine

Name: 1-Acetyl-4-aminopiperidine
Brand: ChemScene
Availability: InStock
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CAS No. 160357-94-8
Cat. No. CS-W008618
Purity≥97%
MDL No.MFCD03412449

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Description

1-Acetyl-4-aminopiperidine is a bench-stable, moisture-tolerant piperidine derivative featuring a strategically positioned acetyl group that enhances solubility and reactivity. This functionalized scaffold integrates readily into medicinal chemistry libraries, enabling efficient access to bioactive analogs through straightforward derivatization pathways.

Application

1-Acetyl-4-aminopiperidine serves as a versatile building block in medicinal chemistry, enabling the construction of diverse piperidine-based scaffolds. The acetyl group provides protection for the amine while maintaining reactivity for subsequent functionalization, and the secondary amine facilitates salt formation and hydrogen bonding. Its bench-stable nature and compatibility with standard coupling and reduction protocols make it well-suited for multi-step synthesis and API development workflows.

General Information

CAS No. 160357-94-8
Cat. No. CS-W008618
Purity ≥97%
MDL No. MFCD03412449
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₄N₂O
Molecular Weight 142.20
Synonym(s) 1-(4-Amino-1-piperidinyl)ethanone; (1-Acetyl-4-piperidinyl)amine; 1-(4-Aminopiperidin-1-yl)ethanone; 4-Amino-N-1-acetylpiperidine
SMILES CC(N1CCC(N)CC1)=O

Computational Chemistry Data

TPSA 46.33
LogP -0.044
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Key Words

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1-Acetyl-4-aminopiperidine

CAS No. 160357-94-8

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