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CS-W001157 4
Total: USD 88.00

2,5-Dibromo-3-chloropyridine

  • CAS No. 160599-70-2

  • Cat. No. CS-D0854
  • Purity≥98%
  • MDL No.MFCD08277306

*For research and further manufacturing use only, not for direct human use.

2,5-Dibromo-3-chloropyridine|CS-D0854

Structure of 160599-70-2

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General Information

  • CAS No. 160599-70-2
  • Cat. No. CS-D0854
  • Purity ≥98%
  • MDL No. MFCD08277306
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₂Br₂ClN
  • Molecular Weight 271.34
  • Synonym(s) Pyridine, 2,5-dibromo-3-chloro-
  • SMILES ClC1=CC(Br)=CN=C1Br

Description

2,5-Dibromo-3-chloropyridine features a highly functionalized pyridine core with bromo and chloro substituents at electron-deficient positions, enabling direct coupling in cross-coupling reactions. This bench-stable heterocycle integrates efficiently into complex molecular architectures under standard conditions.

Application

2,5-Dibromo-3-chloropyridine serves as a versatile building block for constructing substituted pyridine scaffolds in medicinal chemistry and agrochemical synthesis. The ortho-bromine and meta-chlorine substituents enable selective metal-catalyzed cross-coupling reactions, facilitating the assembly of complex heterocyclic architectures with high functional group tolerance. Its bench-stable crystalline form simplifies handling and purification, making it well-suited for iterative synthetic workflows.

Synthesis

  • Route1

    References

    • US5629428 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   3.26
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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