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Structure of 1610705-51-5
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Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2-carboxylate features a boronate ester group that enables efficient Suzuki-Miyaura coupling under mild conditions. The tetramethyl-substituted dioxaborolane enhances stability and solubility in organic solvents. This reagent integrates readily into complex molecular architectures with high functional group tolerance.
Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2-carboxylate serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The pyrimidine core enables access to bioactive heterocycles, while the tetramethylborolane group provides excellent stability, low toxicity, and compatibility with diverse functional groups. This reagent facilitates efficient C–C bond formation under mild conditions, offering reliable yields and simplified purification—ideal for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: