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Structure of 161157-50-2
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tert-Butyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate features a rigid, electron-deficient bicyclic scaffold that integrates a masked amine and a labile ester handle. This configuration enables direct functionalization at the nitrogen center while maintaining stability under standard bench conditions. The oxabicyclic framework imparts conformational constraint ideal for probing stereoselective transformations in synthetic medicinal chemistry.
tert-Butyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate serves as a versatile bicyclic scaffold for medicinal chemistry, enabling access to constrained heterocyclic systems through standard functional group manipulations. The tert-butyl ester facilitates easy deprotection under mild acidic conditions, while the embedded oxazepine core exhibits favorable stability and compatibility with diverse coupling reactions. Its defined stereochemistry and functional group tolerance make it suitable for rapid library synthesis and structure-activity studies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: