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H-Gly-Gly-Gly-OEt.HCl

  • CAS No. 16194-06-2

  • Cat. No. CS-0151532
  • Molecule weight253.68
  • Purity≥95%
  • MDL No.MFCD00237929

*For research and further manufacturing use only, not for direct human use.

H-Gly-Gly-Gly-OEt.HCl|CS-0151532

Structure of 16194-06-2

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General Information

  • CAS No. 16194-06-2
  • Cat. No. CS-0151532
  • Purity ≥95%
  • MDL No. MFCD00237929
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆ClN₃O₄
  • Molecular Weight 253.68
  • Synonym(s) H-Gly-Gly-Gly-OEt hydrochloride
  • SMILES CCOC(CNC(CNC(CN)=O)=O)=O.Cl

Description

H-Gly-Gly-Gly-OEt.HCl is a tripeptide ester featuring a C-terminal ethyl ester and protonated N-terminus, offering enhanced solubility and stability under standard conditions. This derivative facilitates efficient peptide coupling workflows while minimizing side reactions during synthesis.

Application

H-Gly-Gly-Gly-OEt·HCl serves as a stable, bench-ready tripeptide building block for solid-phase and solution-phase peptide synthesis. Its ethyl ester terminus enables straightforward amide bond formation, while the N-terminal H-protecting group ensures compatibility with standard coupling protocols. The hydrochloride salt enhances solubility and handling, facilitating efficient purification and incorporation into larger peptide sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   110.52
  • LogP   -1.8376
  • H_Acceptors   5
  • H_Donors   3
  • Rotatable_Bonds   6

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