2-Chloro-6-fluoro-4-iodopyridine

Name: 2-Chloro-6-fluoro-4-iodopyridine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1622843-82-6
Cat. No. CS-0932891
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

2-Chloro-6-fluoro-4-iodopyridine|CS-0932891

Structure of 1622843-82-6

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Description

2-Chloro-6-fluoro-4-iodopyridine is a halogenated pyridine derivative featuring strategically positioned chlorine, fluorine, and iodine substituents. This electron-deficient heterocycle enables selective cross-coupling reactions under palladium catalysis, serving as a key building block in the synthesis of functionalized pharmaceutical intermediates and advanced materials.

Application

2-Chloro-6-fluoro-4-iodopyridine serves as a versatile building block in cross-coupling chemistry, enabling efficient access to substituted pyridines via Pd-catalyzed reactions. The strategic placement of chlorine, fluorine, and iodine facilitates sequential functionalization, with the iodine group offering high reactivity in Suzuki, Stille, and Negishi couplings. Its bench-stable nature and compatibility with diverse reaction conditions make it well-suited for medicinal chemistry and process development workflows.

General Information

CAS No. 1622843-82-6
Cat. No. CS-0932891
Purity ≥98%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₂ClFIN
Molecular Weight 257.43
Synonym(s) None
SMILES FC1=CC(I)=CC(Cl)=N1

Computational Chemistry Data

TPSA 12.89
LogP 2.4787
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H317-H319
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2-Chloro-6-fluoro-4-iodopyridine

CAS No. 1622843-82-6

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