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6-Aminopyridine-3-sulfonic acid

  • CAS No. 16250-08-1

  • Cat. No. CS-0043744
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-Aminopyridine-3-sulfonic acid|CS-0043744

Structure of 16250-08-1

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General Information

  • CAS No. 16250-08-1
  • Cat. No. CS-0043744
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₆N₂O₃S
  • Molecular Weight 174.18
  • Synonym(s) 2-AMINOPYRIDINE-5-SULFONIC ACID
  • SMILES O=S(C1=CC=C(N)N=C1)(O)=O

Description

6-Aminopyridine-3-sulfonic acid features a pyridine ring bearing both amino and sulfonic acid groups at meta positions, enabling strong hydrogen bonding and enhanced water solubility. This dual functionality supports its use in dye synthesis, pharmaceutical intermediates, and as a chelating agent in coordination chemistry, where the acidic sulfonate group facilitates metal ion binding under physiological conditions.

Application

6-Aminopyridine-3-sulfonic acid serves as a versatile building block for sulfonated heterocycles, enabling direct incorporation of both amine and sulfonic acid functionalities in medicinal chemistry and materials science. Its dual polar groups enhance solubility and facilitate downstream derivatization via amide coupling or electrophilic substitution. Bench-stable and readily purified by recrystallization, it functions effectively in aqueous and mixed solvent systems for API intermediate synthesis and functional polymer development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   93.28
  • LogP   -0.0895
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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