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CS-W001157 4
Total: USD 88.00

PEG2-MeN-Boc

  • CAS No. 1628679-52-6

  • Cat. No. CS-0370537
  • Purity≥97%
  • MDL No.MFCD31557927
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

PEG2-MeN-Boc|CS-0370537

Structure of 1628679-52-6

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Description

tert-Butyl (2-(2-hydroxyethoxy)ethyl)(methyl)carbamate is a bench-stable, moisture-tolerant protecting group reagent designed for selective amine derivatization. This carbamate features a hydrophilic ethylene glycol tether that enhances solubility in polar solvents while maintaining compatibility with standard deprotection protocols. The tert-butyl moiety provides robust protection under mild acidic conditions, enabling efficient release of primary amines without side reactions. Its modular structure supports integration into peptide synthesis and bioconjugation workflows, offering high chemoselectivity and predictable cleavage behavior.

Application

tert-Butyl (2-(2-hydroxyethoxy)ethyl)(methyl)carbamate serves as a versatile bifunctional protecting group reagent, enabling selective protection of primary amines while retaining a pendant hydroxyl for further derivatization. Its tert-butyl carbamate moiety offers robust stability under basic conditions and mild deprotection with trifluoroacetic acid, while the hydroxyethyl side chain facilitates conjugation or orthogonal functionalization in peptide and nucleoside synthesis. The molecule exhibits excellent bench stability, ease of purification, and compatibility with standard coupling protocols.

General Information

  • CAS No. 1628679-52-6
  • Cat. No. CS-0370537
  • Purity ≥97%
  • MDL No. MFCD31557927
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₁NO₄
  • Molecular Weight 219.28
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)N(C)CCOCCO

Computational Chemistry Data

  • TPSA   59
  • LogP   0.8622
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   5

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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