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Structure of 1628679-52-6
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tert-Butyl (2-(2-hydroxyethoxy)ethyl)(methyl)carbamate is a bench-stable, moisture-tolerant protecting group reagent designed for selective amine derivatization. This carbamate features a hydrophilic ethylene glycol tether that enhances solubility in polar solvents while maintaining compatibility with standard deprotection protocols. The tert-butyl moiety provides robust protection under mild acidic conditions, enabling efficient release of primary amines without side reactions. Its modular structure supports integration into peptide synthesis and bioconjugation workflows, offering high chemoselectivity and predictable cleavage behavior.
tert-Butyl (2-(2-hydroxyethoxy)ethyl)(methyl)carbamate serves as a versatile bifunctional protecting group reagent, enabling selective protection of primary amines while retaining a pendant hydroxyl for further derivatization. Its tert-butyl carbamate moiety offers robust stability under basic conditions and mild deprotection with trifluoroacetic acid, while the hydroxyethyl side chain facilitates conjugation or orthogonal functionalization in peptide and nucleoside synthesis. The molecule exhibits excellent bench stability, ease of purification, and compatibility with standard coupling protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: