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Structure of 1630906-91-0
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This difluorinated spirocyclic amine, featuring a constrained five-membered ring with nitrogen and two fluorine atoms, delivers enhanced metabolic stability and improved membrane permeability. The hydrochloride salt form ensures high solubility and crystalline purity, enabling straightforward handling in medicinal chemistry workflows.
1,1-Difluoro-5-azaspiro[2.3]hexane hydrochloride serves as a conformationally constrained difluoromethylated azaspiro scaffold, enabling access to fluorinated bioactive molecules through standard amine functionalization and coupling reactions. Its bench-stable hydrochloride salt facilitates handling and purification, while the spirocyclic framework provides defined stereochemistry and enhanced metabolic stability in medicinal chemistry applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: