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Structure of 1637671-24-9
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6-Chloro-2-methylpyrido[3,4-d]pyrimidin-4(1H)-one features a fused pyridopyrimidinone core with strategic chlorine and methyl substitutions. This electron-deficient heterocycle integrates readily into medicinal chemistry scaffolds, offering enhanced metabolic stability and favorable binding interactions in kinase-targeted drug discovery.
6-Chloro-2-methylpyrido[3,4-d]pyrimidin-4(1H)-one serves as a versatile building block for purine-derived scaffolds in medicinal chemistry. The chloro group at C6 enables nucleophilic substitution reactions, while the 2-methyl and lactam functionalities provide orthogonal reactivity for downstream functionalization. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for modular synthesis of kinase inhibitors and other bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: