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(2-Methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)methanamine

  • CAS No. 1638760-94-7

  • Cat. No. CS-0476506
  • Molecule weight161.20
  • Purity≥95%
  • MDL No.MFCD26521683

*For research and further manufacturing use only, not for direct human use.

(2-Methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)methanamine|CS-0476506

Structure of 1638760-94-7

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General Information

  • CAS No. 1638760-94-7
  • Cat. No. CS-0476506
  • Purity ≥95%
  • MDL No. MFCD26521683
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁N₃
  • Molecular Weight 161.20
  • Synonym(s) None
  • SMILES CC1=CC2=C(CN)C=CN=C2N1

Description

This boronate moiety integrates seamlessly into Suzuki-Miyaura coupling reactions, offering enhanced reactivity and stability under standard conditions. The electron-rich pyrrolopyridine scaffold enables efficient cross-coupling with aryl halides, while the pendant amine group facilitates downstream functionalization through amide bond formation or conjugation chemistry.

Application

(2-Methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)methanamine serves as a versatile building block for medicinal chemistry, enabling efficient access to pyrrolopyridine-based scaffolds. Its primary amine functionality facilitates straightforward derivatization via amidation, alkylation, and reductive amination. The molecule exhibits good bench stability and compatibility with standard purification methods, supporting its use in multi-step synthesis and high-throughput screening campaigns.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3259
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H314-H318-H335
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   54.7
  • LogP   1.33002
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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