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Structure of 1642542-05-9
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1-Bromo-5-chloro-3-fluoro-2-nitrobenzene offers a trifunctional aryl scaffold with orthogonal reactivity, enabling sequential cross-coupling and nucleophilic substitution. The electron-deficient ring facilitates efficient palladium-catalyzed transformations, while the halogen array supports modular derivatization in medicinal chemistry and materials synthesis.
1-Bromo-5-chloro-3-fluoro-2-nitrobenzene serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its reactive aryl halide functionality. The presence of multiple electron-withdrawing substituents enhances electrophilicity for nucleophilic aromatic substitution, while the nitro group provides a handle for downstream reduction and functionalization. Bench-stable and compatible with standard purification methods, it facilitates efficient construction of complex heterocyclic scaffolds and multi-substituted aromatic systems in industrial R&D workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: