1-Methyl-3-((methylamino)methyl)-1H-pyrazole-5-carbonitrile hydrochloride

Name: 1-Methyl-3-((methylamino)methyl)-1H-pyrazole-5-carbonitrile hydrochloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1643141-20-1
Cat. No. CS-0101072
Purity≥98%
MDL No.MFCD31697852

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-Methyl-3-((methylamino)methyl)-1H-pyrazole-5-carbonitrile hydrochloride|CS-0101072

Structure of 1643141-20-1

Size

Price

Quantity

* Please select Quantity before adding items.

Description

This pyrazole derivative features a methylamino-methyl substituent at the 3-position and a nitrile group at the 5-position, delivering enhanced solubility and metabolic stability. The hydrochloride salt form ensures improved crystallinity and handling ease. This scaffold integrates readily into bioactive molecules for medicinal chemistry applications, particularly in kinase inhibitor design and CNS-targeted drug discovery.

Application

1-Methyl-3-((methylamino)methyl)-1H-pyrazole-5-carbonitrile hydrochloride serves as a versatile pyrazole-based building block for medicinal chemistry and heterocyclic synthesis. The molecule combines a nitrile group at the C5 position with a methylamino-methyl substituent at C3, enabling further functionalization via nucleophilic or electrophilic reactions. Its hydrochloride salt enhances solubility and stability, facilitating handling and purification in standard bench-scale applications. Functions effectively in coupling reactions and as a scaffold for targeted compound libraries.

General Information

CAS No. 1643141-20-1
Cat. No. CS-0101072
Purity ≥98%
MDL No. MFCD31697852
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₁ClN₄
Molecular Weight None
Synonym(s) 1-methyl-3-((methylamino)methyl)-1H-pyrazole-5-carbonitrilehydrochloridesalt
SMILES N#CC1=CC(CNC)=NN1C.[H]Cl

Computational Chemistry Data

TPSA 53.64
LogP 0.43298
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Cyanide/Nitrile

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazole compounds

Key Words

1643141-20-1 sigma1643141-20-1 manufacturer1643141-20-1 price1643141-20-1 structure1643141-20-1 SDSbuy 1643141-20-11643141-20-1 supplier1643141-20-1 uses1643141-20-1 molecular weightprice of 1643141-20-11643141-20-1 chemical name formula of 1643141-20-1

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1-Methyl-3-((methylamino)methyl)-1H-pyrazole-5-carbonitrile hydrochloride

CAS No. 1643141-20-1

Recommended Products