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Structure of 1646-54-4
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1,4-Dibromo-2,3,5,6-tetramethylbenzene features a sterically hindered aromatic core with bromine substituents at the para positions, enabling selective cross-coupling reactions. The four methyl groups enhance solubility and stability under standard conditions, while the electron-deficient ring facilitates palladium-catalyzed transformations. This compound serves as a robust building block for functionalized arenes in synthetic organic chemistry.
1,4-Dibromo-2,3,5,6-tetramethylbenzene serves as a versatile dibrominated aromatic building block for the synthesis of functionalized biaryls and heterocycles. Its sterically encumbered structure enhances stability and facilitates selective cross-coupling reactions under standard Pd-catalyzed conditions. The molecule’s defined substitution pattern enables predictable regiochemistry in Suzuki-Miyaura and Stille couplings, while its crystalline form simplifies purification and handling in industrial-scale syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: