Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Iodoquinoline

  • CAS No. 16560-43-3

  • Cat. No. CS-0041400
  • Purity≥97%
  • MDL No.MFCD07700252

*For research and further manufacturing use only, not for direct human use.

4-Iodoquinoline|CS-0041400

Structure of 16560-43-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 16560-43-3
  • Cat. No. CS-0041400
  • Purity ≥97%
  • MDL No. MFCD07700252
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆IN
  • Molecular Weight 255.06
  • Synonym(s) 4-Iodo-1-azanaphthalene
  • SMILES IC1=CC=NC2=CC=CC=C12

Description

4-Iodoquinoline is a bench-stable heterocyclic compound featuring a iodine atom at the 4-position of the quinoline core. This substitution enables efficient cross-coupling reactions, facilitating the construction of complex biaryl architectures in medicinal chemistry and materials science applications.

Application

4-Iodoquinoline serves as a versatile building block in medicinal chemistry and cross-coupling synthesis, enabling efficient palladium-catalyzed transformations such as Suzuki, Stille, and Buchwald-Hartwig reactions. Its iodine substituent provides high reactivity under standard conditions, while the quinoline core offers favorable electronic properties and metabolic stability. The compound exhibits excellent bench stability and ease of purification, making it well-suited for scalable synthesis and modular scaffold development in API discovery workflows.

Synthesis

  • Route1

    References

    • Dumouchel, Sylvain; Mongin, Florence; Trecourt, Francois; Queguiner, Guy Tetrahedron, 2003 , vol. 59, # 43 p. 8629 - 8640
  • Route2

    References

    • US2002/19527 A1, ;
  • Route3
    • null|null
      79476-06-5
    • ~93%
    • In-stock
      4-Iodoquinoline|CS-0041400
      16560-43-3

    References

    • Yamamoto, Yutaka; Yanagi, Akihiko Heterocycles, 1981 , vol. 16, # 7 p. 1161 - 1164

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.8394
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Iodoquinoline sigma4-Iodoquinoline manufacturer4-Iodoquinoline price4-Iodoquinoline structure4-Iodoquinoline SDSbuy 4-Iodoquinoline4-Iodoquinoline supplier4-Iodoquinoline uses4-Iodoquinoline molecular weightprice of 4-Iodoquinoline4-Iodoquinoline chemical name formula of 4-Iodoquinoline
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label