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CS-W001157 4
Total: USD 88.00

6-Bromo-4-iodoquinoline

  • CAS No. 927801-23-8

  • Cat. No. CS-M0127
  • Purity≥97%
  • MDL No.MFCD08437008
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Bromo-4-iodoquinoline|CS-M0127

Structure of 927801-23-8

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Description

6-Bromo-4-iodoquinoline is a dual-halogenated quinoline scaffold enabling efficient cross-coupling transformations in medicinal chemistry. The strategically positioned bromo and iodo groups facilitate sequential Pd-catalyzed reactions, allowing rapid diversification at distinct ring positions. This ortho-selective halogen arrangement supports modular synthesis of complex heterocyclic architectures under standard conditions.

Application

6-Bromo-4-iodoquinoline serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling the construction of biaryl and heteroaryl scaffolds. The orthogonal reactivity of bromo and iodo substituents facilitates sequential functionalization under standard Pd-catalyzed conditions. Its bench-stable nature and compatibility with diverse reaction partners make it well-suited for medicinal chemistry and process development workflows.

General Information

  • CAS No. 927801-23-8
  • Cat. No. CS-M0127
  • Purity ≥97%
  • MDL No. MFCD08437008
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₅BrIN
  • Molecular Weight 333.95
  • Synonym(s) T66 BNJ EI HE
  • SMILES IC1=CC=NC2=C1C=C(Br)C=C2

Computational Chemistry Data

  • TPSA   12.89
  • LogP   3.6019
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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