Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH

Name: Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH
Brand: ChemScene
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CAS No. 1662688-20-1
Cat. No. CS-0699032
Purity≥96%
MDL No.MFCD34563738

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH|CS-0699032

Structure of 1662688-20-1

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General Information

CAS No. 1662688-20-1
Cat. No. CS-0699032
Purity ≥96%
MDL No. MFCD34563738
Storage -20°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆₄H₁₀₁N₅O₁₆
Molecular Weight 1196.51
Synonym(s) None
SMILES CC(C)(C)OC(=O)CCCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)NCCCC[C@H](NC(=O)OCC1C2=CC=CC=C2C2=CC=CC=C12)C(O)=O)C(=O)OC(C)(C)C

Description

Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH is a multifunctional peptide building block featuring a C-terminal AEEA-AEEA extension and dual (OtBu)-protected glutamic acid side chains. This design enables efficient solid-phase synthesis of complex, densely functionalized peptides with enhanced solubility and stability during purification.

Application

Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH serves as a versatile, multi-functional building block for solid-phase peptide synthesis, enabling the construction of complex peptide architectures with enhanced solubility and controlled side-chain functionality. The octyl (Oct) and tert-butyl (OtBu) protected glutamate residues provide steric shielding and orthogonal protection, while the AEEA-AEEA spacer ensures flexibility and efficient coupling. Bench-stable and compatible with standard Fmoc protocols, it facilitates reliable purification and scalable synthesis of bioactive peptides and conjugates.

Safety Information

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GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H413
Precautionary Statements : P273-P501

Quality Control

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Computational Chemistry Data

TPSA 281.55
LogP 8.7536
H_Acceptors 15
H_Donors 6
Rotatable_Bonds 47

Other Classifications

Building Blocks Functional Group Boc

Building Blocks Functional Group Fmoc

Building Blocks Functional Group Ether

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Key Words

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Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH

CAS No. 1662688-20-1

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