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CS-W001157 4
Total: USD 88.00

3-(3-Aminophenyl)propanoic acid

  • CAS No. 1664-54-6

  • Cat. No. CS-W005084
  • Purity≥97%
  • MDL No.MFCD00153889

*For research and further manufacturing use only, not for direct human use.

3-(3-Aminophenyl)propanoic acid|CS-W005084

Structure of 1664-54-6

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General Information

  • CAS No. 1664-54-6
  • Cat. No. CS-W005084
  • Purity ≥97%
  • MDL No. MFCD00153889
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁NO₂
  • Molecular Weight 165.19
  • Synonym(s) 3-Aminophenylpropanoic Acid
  • SMILES O=C(O)CCC1=CC=CC(N)=C1

Description

This 3-(3-Aminophenyl)propanoic acid features a para-aminophenyl group linked via a propionic acid chain, enabling integration into bioconjugation workflows. The amine and carboxylic acid functionalities offer dual reactivity for coupling to biomolecules or solid supports under standard conditions.

Application

3-(3-Aminophenyl)propanoic acid serves as a versatile building block for pharmaceutical and agrochemical synthesis, enabling efficient access to bioactive heterocycles and peptide-like scaffolds. The ortho-aminobenzoic acid motif facilitates direct functionalization and cyclization reactions, while the aliphatic carboxylic acid group supports amide coupling and derivatization under standard conditions. Its bench-stable nature and compatibility with diverse reaction environments make it well-suited for iterative synthesis workflows in medicinal chemistry and process development.

Synthesis

  • Route1

    References

    • Chemische Berichte, , vol. 15, p. 846
  • Route2

    References

    • Carnazzi; Aumelas; Barberis; Guillon; Seyer Journal of Medicinal Chemistry, 1994 , vol. 37, # 12 p. 1841 - 1849
  • Route3
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    References

    • US4769447 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   1.286
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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