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Structure of 16694-18-1
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4-Bromo-thiophene-2-carboxylic acid features a bromine substituent at the 4-position of a thiophene ring, delivering enhanced reactivity for cross-coupling transformations. The carboxylic acid group enables direct derivatization or integration into bioactive scaffolds. This bench-stable, moisture-tolerant compound serves as a key building block in medicinal chemistry and materials science.
4-Bromo-thiophene-2-carboxylic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. The bromo group enables palladium-catalyzed cross-coupling reactions, while the carboxylic acid functionality facilitates amide formation, esterification, and direct derivatization. Its bench-stable nature and compatibility with standard synthetic protocols make it well-suited for iterative functionalization in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: