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Structure of 167275-44-7
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8-Bromonaphthalen-2-amine features a bromine atom at the 8-position of the naphthalene core, paired with a primary amine group at the 2-position. This configuration enables selective functionalization in cross-coupling reactions and facilitates integration into conjugated systems for materials science applications. The molecule exhibits enhanced stability under standard handling conditions and demonstrates compatibility with palladium-catalyzed transformations.
8-Bromonaphthalen-2-amine serves as a valuable building block for the synthesis of functionalized naphthalene derivatives, enabling efficient Suzuki-Miyaura and Buchwald-Hartwig coupling reactions. Its bromine substituent provides high reactivity in palladium-catalyzed cross-couplings, while the primary amine offers a versatile handle for further derivatization. The compound exhibits excellent bench stability and is readily purified by recrystallization, making it well-suited for scalable synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: