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Structure of 16744-81-3
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4-Methoxypicolinaldehyde features a pyridine ring with strategically positioned aldehyde and methoxy groups, enabling selective reactivity in cross-coupling and condensation reactions. This bench-stable, moisture-tolerant reagent integrates readily into synthetic pathways requiring electron-deficient heteroaryl platforms.
4-Methoxypicolinaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyridine-based heterocycles. Its aldehyde functionality facilitates reductive amination, Ugi-type condensations, and coupling reactions with nucleophiles under mild conditions. The methoxy group enhances solubility and modulates electronic properties, while the compound exhibits good bench stability and ease of purification—making it suitable for high-throughput synthesis and scale-up applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: