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CS-W001157 4
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5-Methoxypicolinaldehyde

  • CAS No. 22187-96-8

  • Cat. No. CS-W005343
  • Molecule weight137.14
  • Purity≥98%
  • MDL No.MFCD08234867

*For research and further manufacturing use only, not for direct human use.

5-Methoxypicolinaldehyde|CS-W005343

Structure of 22187-96-8

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General Information

  • CAS No. 22187-96-8
  • Cat. No. CS-W005343
  • Purity ≥98%
  • MDL No. MFCD08234867
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇NO₂
  • Molecular Weight 137.14
  • Synonym(s) 5-Methoxypyridine-2-carboxaldehyde
  • SMILES O=CC1=NC=C(OC)C=C1

Description

5-Methoxypicolinaldehyde delivers a strategically positioned methoxy group that enhances solubility and modulates electronic properties in synthetic transformations. This bench-stable aldehyde features a pyridine ring with optimized reactivity, enabling efficient coupling reactions in complex molecule assembly.

Application

5-Methoxypicolinaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyridine-based heterocycles and bioactive scaffolds. Its aldehyde functionality facilitates reductive amination, imine formation, and coupling reactions under mild conditions. The methoxy group enhances solubility and modulates electronic properties, while the compound exhibits excellent bench stability and ease of purification—key attributes for high-throughput synthesis and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   39.19
  • LogP   0.9027
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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