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CS-W001157 4
Total: USD 88.00

2-Aminoquinazoline

  • CAS No. 1687-51-0

  • Cat. No. CS-W009159
  • Purity≥97%
  • MDL No.MFCD00956186
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Aminoquinazoline|CS-W009159

Structure of 1687-51-0

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Description

2-Aminoquinazoline serves as a core scaffold in medicinal chemistry, offering a rigid, electron-rich heterocyclic platform for drug discovery. This bench-stable compound integrates readily into kinase inhibitors and targeted therapeutics, where its amino group enables direct functionalization and hydrogen bonding interactions critical to binding affinity.

Application

2-Aminoquinazoline serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to kinase inhibitors and other bioactive scaffolds. Its amino group facilitates direct functionalization and metal-catalyzed coupling reactions, while the quinazoline core exhibits favorable stability and solubility for downstream derivatization. The compound functions as a key intermediate in the synthesis of targeted therapeutics and is well-suited for parallel library generation due to its predictable reactivity and compatibility with standard synthetic protocols.

General Information

  • CAS No. 1687-51-0
  • Cat. No. CS-W009159
  • Purity ≥97%
  • MDL No. MFCD00956186
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇N₃
  • Molecular Weight 145.16
  • Synonym(s) 2-Aminoquinazoline; Quinazolin-2-ylamine
  • SMILES NC1=NC=C2C=CC=CC2=N1

Computational Chemistry Data

  • TPSA   51.8
  • LogP   1.212
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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