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Structure of 16879-53-1
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2-Phenylpyrimidine-4-carboxylic acid features a rigid, electron-deficient pyrimidine core functionalized with a phenyl group and a carboxylic acid moiety, enabling direct integration into pharmaceutical scaffolds. This structural motif supports hydrogen bonding and dipole interactions, enhancing target binding affinity in kinase inhibitors and other bioactive molecules.
2-Phenylpyrimidine-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling reactions. Its well-defined functional group pattern—aryl, pyrimidine, and carboxylic acid—facilitates direct derivatization via amide, ester, or amidation protocols. The compound exhibits good bench stability and compatibility with common reaction conditions, supporting efficient synthesis of pharmaceutical candidates and functional materials.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: