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Structure of 169674-35-5
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5,6-Difluoro-1H-indole-2-carboxylic acid features a fluorinated indole core with electron-withdrawing substituents at the 5 and 6 positions, enhancing metabolic stability and modulating electronic properties. This scaffold integrates readily into bioactive molecules, offering improved membrane permeability and resistance to oxidative degradation in medicinal chemistry applications.
5,6-Difluoro-1H-indole-2-carboxylic acid serves as a valuable building block for the synthesis of fluorinated heterocyclic compounds. Its ortho-fluorine substituents enhance metabolic stability and modulate electronic properties, enabling efficient coupling reactions in peptide and medicinal chemistry workflows. The carboxylic acid functionality facilitates direct derivatization or salt formation, offering excellent bench stability and compatibility with standard purification protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: