Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

7-Fluoro-1H-indole-2-carboxylic acid

  • CAS No. 399-67-7

  • Cat. No. CS-W005660
  • Molecule weight179.15
  • Purity≥97%
  • MDL No.MFCD02664429

*For research and further manufacturing use only, not for direct human use.

7-Fluoro-1H-indole-2-carboxylic acid|CS-W005660

Structure of 399-67-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 399-67-7
  • Cat. No. CS-W005660
  • Purity ≥97%
  • MDL No. MFCD02664429
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆FNO₂
  • Molecular Weight 179.15
  • Synonym(s) 7-Fluoro-1H-indole-2-carboxylicacid
  • SMILES O=C(C(N1)=CC2=C1C(F)=CC=C2)O

Description

7-Fluoro-1H-indole-2-carboxylic acid features a fluorinated indole core with a carboxylic acid group at the 2-position, enabling direct incorporation into bioactive molecule scaffolds. The electron-withdrawing fluorine substituent enhances metabolic stability and modulates electronic properties, while the carboxylic acid provides a versatile handle for amide coupling or salt formation under standard conditions.

Application

7-Fluoro-1H-indole-2-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation of a fluoro-substituted indole scaffold into bioactive molecules. The carboxylic acid functionality facilitates amide coupling, esterification, and metal-catalyzed transformations under standard conditions. Its bench-stable nature and compatibility with diverse functional groups support efficient synthesis of heterocyclic compounds and API intermediates.

Synthesis

  • Route1

    References

    • Allen et al. Journal of the Chemical Society, 1955 , p. 1283,1284
  • Route2
    • null|null
      349-39-3
    • ~%
    • In-stock
      7-Fluoro-1H-indole-2-carboxylic acid|CS-W005660
      399-67-7

    References

    • Allen et al. Journal of the Chemical Society, 1955 , p. 1283,1284
  • Route3
    • null|null
      53559-92-5
    • ~%
    • In-stock
      7-Fluoro-1H-indole-2-carboxylic acid|CS-W005660
      399-67-7

    References

    • Allen et al. Journal of the Chemical Society, 1955 , p. 1283,1284

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   53.09
  • LogP   2.0052
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 7-Fluoro-1H-indole-2-carboxylic acid sigma7-Fluoro-1H-indole-2-carboxylic acid manufacturer7-Fluoro-1H-indole-2-carboxylic acid price7-Fluoro-1H-indole-2-carboxylic acid structure7-Fluoro-1H-indole-2-carboxylic acid SDSbuy 7-Fluoro-1H-indole-2-carboxylic acid7-Fluoro-1H-indole-2-carboxylic acid supplier7-Fluoro-1H-indole-2-carboxylic acid uses7-Fluoro-1H-indole-2-carboxylic acid molecular weightprice of 7-Fluoro-1H-indole-2-carboxylic acid7-Fluoro-1H-indole-2-carboxylic acid chemical name formula of 7-Fluoro-1H-indole-2-carboxylic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label