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Structure of 1701434-52-7
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This boronate-functionalized pyrimidine integrates readily into Suzuki-Miyaura coupling reactions under standard conditions, delivering trifluoromethyl-substituted heterocycles with high efficiency. The tetramethylborolane group ensures excellent stability and compatibility in synthetic workflows.
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyrimidine serves as a versatile boronate building block for palladium-catalyzed cross-coupling reactions. Its trifluoromethylpyrimidine core provides enhanced metabolic stability and favorable electronic properties, making it valuable in medicinal chemistry. The pinacol boronate moiety offers excellent bench stability, mild reaction conditions, and compatibility with diverse functional groups, enabling efficient construction of complex heterocyclic scaffolds in drug discovery workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: